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filingDate 2001-04-27-04:00^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_1b65d5d1d37fe9bb58714050a68f0014
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publicationDate 2002-10-31-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber DE-10120819-A1
titleOfInvention Process for the preparation of 4-trifluoromethylnicotin nitrile
abstract 4-Trifluoromethylnicotinitrile (I) is suitable as an intermediate in the manufacture of pesticides and is obtainable by a process, DOLLAR A, where DOLLAR A a) 4-amino-1,1,1-trifluoro-3-buten-2-one DOLLAR A CF¶3¶-C (O) -CH = CH-NH¶2¶ (II) DOLLAR A in a condensation reaction with a compound of the formulas (III) to (VII), DOLLAR A (RZ) CH = CH-CN (III) DOLLAR A (RZ) ¶2¶CH-CH¶2¶-CN (IV) DOLLAR A Hal-CH = CH-CN (V) DOLLAR A Hal¶2¶CH-CH¶2¶CN (VI) DOLLAR A HC IDENTICAL C-CN (VII) DOLLAR A where R is alkyl, Hal Cl or Br and ZO, S or OCO (alkyl), in which in the case of formula (IV) the last two radicals Z independently of one another are the aforementioned Can assume meanings, DOLLAR A converts to a compound of the formulas (VIII), (IX) and / or (X), DOLLAR A CF¶3¶-C (O) -CH = CH-NH-CH = CH-CN ( VIII) DOLLAR A CF¶3¶-C (O) -CH = CH-NH-CH (ZR) -CH¶2¶-CN (IX) DOLLAR A CF¶3¶-C (O) -CH = CH- NH-CH (Hal) -CH¶2¶-CN (X) DOLLAR A where R, Z and Hal are the above n have the meanings indicated, DOLLAR A and the reaction product DOLLAR A b) are subject to a ring closure reaction. DOLLAR F1
priorityDate 2001-04-27-04:00^^<http://www.w3.org/2001/XMLSchema#date>
type http://data.epo.org/linked-data/def/patent/Publication

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