http://rdf.ncbi.nlm.nih.gov/pubchem/patent/DE-10102265-C1
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_4dac022280ec96f54c694eb427655932 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D271-113 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D413-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D413-12 |
| classificationIPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D271-10 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D413-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D413-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D271-113 |
| filingDate | 2001-01-18-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2002-08-08-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_3c5388caea15f071e62760ce2e288814 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_1dd2ce16fcac4548dfd35dfb2f67721b http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_ba9695f185ed54d131f8bbad733c8435 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_c3ecc2fc35721d07e009c382a2d67427 |
| publicationDate | 2002-08-08-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | DE-10102265-C1 |
| titleOfInvention | Substituted 3-phenyl-5-alkoxi-1,3,4-oxdiazol-2-ones, their production and use in pharmaceuticals |
| abstract | Substituted 3-phenyl-5-alkoxi-1,3,4-oxdiazol-2-ones of the formula 1 are described, DOLLAR F1 in which R · 1 · substituted C¶1¶-C¶6¶-alkyl and C¶3 ¶-C¶9¶-cycloalkyl, R · 2 ·, R · 3 ·, R · 4 · and R · 5 · hydrogen, halogen, nitro, C¶1¶-C¶4¶-alkyl, C¶1¶ -C¶9¶-alkyloxy, substituted C¶6¶-C¶10¶-aryl-C¶1¶-C¶4¶-alkyloxy, C¶6¶-C¶10¶-aryloxy, C¶6¶- C¶10¶-aryl, C¶3¶-C¶8¶-cycloalkyl or OC¶3¶-C¶8¶-cycloalkyl, or 2-oxo-pyrrolidin-1-yl, 2,5-dimethylpyrrol-1- yl or NR · 6 · -AR · 7 ·, with the proviso that R · 2 ·, R · 3 ·, R · 4 · and R · 5 · do not simultaneously represent hydrogen and at least one of the radicals R · 2 · R · 3 ·, R · 4 · or R · 5 · represents the remainder 2-oxo-pyrrolidin-1-yl, 2,5-dimethylpyrrol-1-yl or NR · 6 · -AR · 7 ·, with R6 · = hydrogen, C¶1¶-C¶4¶-alkyl or substituted C¶6¶-C¶10¶-aryl-C¶1¶-C¶4¶-alkyl, A = a single bond , CO¶n¶, SO¶n¶ or CONH, n = 1 or 2, R · 7 · = hydrogen, substituted C ¶1¶-C¶18¶-alkyl, C¶2¶-C¶18¶-alkenyl, C¶6¶-C¶10¶-aryl-C¶1¶-C¶4¶-alkyl, C¶5 ¶-C¶8¶-Cycloalkyl-C¶1¶-C¶4¶-alkyl, C¶5¶-C¶8¶-Cycloalkyl, C¶6¶-C¶10¶-Aryl-C¶2¶- C¶6¶-alkenyl, C¶6¶-C¶10¶-aryl, diphenyl, diphenyl-C¶1¶-C¶4¶-alkyl, indanyl, or the group Het- (CH¶2¶) ¶r ¶-, with r = 0, 1, 2 or 3 and Het = saturated or unsaturated 5-7-membered heterocycle, which can be benzo-fused and substituted, and a process for their preparation. The compounds show an inhibitory effect on the hormone-sensitive lipase, HSL. |
| priorityDate | 2001-01-18-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 230.