http://rdf.ncbi.nlm.nih.gov/pubchem/patent/DE-10057014-A1
Outgoing Links
Predicate | Object |
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assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_78888510358cbfb06e82abb682f53f1d |
classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2710-10345 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2740-13045 |
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K48-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K48-0058 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-86 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-63 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-63 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-861 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K48-00 |
filingDate | 2000-11-17-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationDate | 2002-05-29-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | DE-10057014-A1 |
titleOfInvention | Process for the production of target cell-specific drugs |
abstract | The present invention relates to a method for producing a target cell-specific medicament, comprising the steps: (a) identification of at least two genes whose expression in a target cell is increased compared to expression in a control cell; (b) identification and isolation of the expression control sequences of the at least two genes identified in step (a); (c) Cloning the at least two expression control sequences or functionally equivalent derivatives thereof isolated in step (b) into at least one gene transfer vector, so that the at least two expression control sequences or derivatives in the at least one gene transfer vector each allow regulation of the expression of a sequence, the sequences in Ribonucleic acids are transcribable that functionally interact or encode (poly) peptides that functionally interact; and (d) formulating the at least one gene transfer vector generated in step (c) in a pharmaceutical. The present invention also relates to a medicament which can be obtained by the process according to the invention. The present invention also relates to the use of the at least one gene transfer vector, as defined above, for the manufacture of a medicament for the prophylactic and / or therapeutic treatment of cancer, atherosclerosis, fibrosis, an autoimmune disease, virus-infected cells or psoriasis. In addition, the present ... |
priorityDate | 2000-11-17-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 447.