| abstract |
A process is provided for the preparation of 4- (17alpha-substituted-3-oxoestra-4,9-dien-11beta-yl) benzaldehyde DOLLAR A (1E or 1Z) oximes of the general formula (I) DOLLAR F1, DOLLAR A where R¶1¶ represents a hydrogen atom, a C¶1-6¶ alkyl radical or a C¶n¶F¶2n + 1¶ radical, R¶2¶ represents a C¶1-4¶ alkyl radical, X is an E or Z group OH and Y is an OC¶1-6¶ alkyl group, SC¶1-6¶ alkyl group or OCH¶2¶C¶n¶F¶2n + 1¶ group, where n is 1, 2 or 3, which provides the target compounds of formula (I) in high yield and selectivity. |