| abstract |
The invention relates to a process for the preparation of 4- (17alpha-methyl-substituted-3-oxoestra-4,9-dien-11beta-yl) benzaldehyde DOLLAR A (1E or 1Z) oximes of the general formula (I) DOLLAR F1 wherein R¶1¶ is a hydrogen atom, a C¶1-6¶ alkyl radical or a C¶n¶F¶2n + 1¶ radical, where n is 1, 2 or 3, R¶2¶ is a C¶1 Is -4¶-alkyl, X is an E or Z OH group and Y is an OC¶1-6¶ alkyl group, SC¶1-6¶ alkyl group or OCH¶2¶C¶n¶F¶ 2n + 1¶ group, where n is 1, 2 or 3, which provides the target compounds of formula (I) with high yield and selectivity. |