http://rdf.ncbi.nlm.nih.gov/pubchem/patent/DE-10049732-A1
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_833ab853148a9e9715a0e4920e7d7e80 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-80 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-5014 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-50 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-80 |
| filingDate | 2000-09-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_b90f1cd17e7e0624487d03a2978eb3d4 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_a43f3ee533ba81740a849e92bb9d020c |
| publicationDate | 2002-04-18-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | DE-10049732-A1 |
| titleOfInvention | Method for testing substances with lytic activity, arrangement for carrying out and using the method |
| abstract | Known test methods are based on the basic principle of lysis (dissolution of the cell structure) of erythrocytes and subsequent photometric determination of the released hemoglobin by measuring the absorption of light of a predetermined wavelength. However, the known methods are carried out in individual and larger reaction vessels and cuvettes with individual measurements. The amount of equipment to be used, the substance to be tested and, above all, the processing and testing time to achieve meaningful results is very high. The method (ELA) according to the invention is based on the lysis detection principle, but introduces a highly efficient parallel processing of the substance to be tested (TS, AP) in mul-small individual volumes of different training forms (CV, SV), which are in the form of a matrix (MPC, MPV) can be arranged. This results in a high sample throughput combined with a correspondingly high process economy and safety. In embodiments, the method according to the invention operates at an absorption wavelength of 414 nm, as a result of which a sensitivity which is approximately ten times greater than that of known methods is achieved. The method according to the invention can be easily automated and thus implemented commercially in applications both as a test system, as an early warning system or as a screening system. |
| priorityDate | 2000-09-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 22.