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filingDate 2000-06-03-04:00^^<http://www.w3.org/2001/XMLSchema#date>
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publicationDate 2001-12-06-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber DE-10027654-A1
titleOfInvention Process for the preparation of isomerically pure 4-methyl acetophenone
abstract Process for the preparation of isomerically pure 4-methylacetophenone of the formula (I), DOLLAR F1 by reacting p-tolylmagnesium halide in suitable ethers with acetic anhydride at a temperature in the range from -40 ° C. to +10 ° C., followed by a suitable workup of the reaction solution and separation of 4-methyl acetophenone. DOLLAR A The concentration of the Grignard solution used is preferably in the range from 5 to 40% by weight.
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