| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_c86fca830dc13d3de936a7cc1ee3a710 |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N1-36 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-52 |
| classificationIPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N1-36 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-52 |
| filingDate |
2000-05-03-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_8d429f63ac47e6157e32db06b1109014 |
| publicationDate |
2001-11-15-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
DE-10021390-A1 |
| titleOfInvention |
Protection solution and fixation method for the paraffin section technique |
| abstract |
Although formaldehyde can be used for histological applications due to its very good morphological structure maintenance, the requirements for tissue fixation have increased recently due to the development of modern molecular biological methods. When used with immunohistochemical and molecular genetic methods, a number of disadvantages of the formaldehyde-fixed samples have been shown, since the protein-crosslinking effect of formaldehyde has proven to be disadvantageous for direct studies on the protein structures. The invention therefore provides a protection solution which is characterized in that it contains at least one amino acid and at least one sugar compound. the nitrogen compounds are preferably amino acids such as glycine, L-alanine, L-proline, L-serine and / or L-glutamic acid. The sugar compound is preferably D-glucose. The invention also encompasses a method in which a solvent (eg acetone) is added directly after treatment with the protection solution. The protection solution can e.g. B. can be easily prepared from tablets. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2015080585-A1
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| priorityDate |
2000-05-03-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |