http://rdf.ncbi.nlm.nih.gov/pubchem/patent/DE-10021267-A1
Outgoing Links
Predicate | Object |
---|---|
assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_b1b4831f3b6f521a1b67902071918901 |
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-52 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-64 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-66 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N1-21 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-52 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-66 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-64 |
filingDate | 2000-04-26-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_61ea1354f0c5c62139c052c5898be871 |
publicationDate | 2002-01-24-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | DE-10021267-A1 |
titleOfInvention | Process for the production of modular enzyme systems by synthesis of their genes in cyclically repeatable synthesis steps |
abstract | The invention relates to a method for the production of new modularly constructed enzyme systems by genetic engineering, which is characterized by a cyclic in vitro gene synthesis and enables a specific recombination of the individual, gene-coded modular components to form new enzyme systems. Such modularly constructed enzyme systems are, for example, the non-ribosomal peptide synthase (NRPS) or polyketide synthase (PKS) of type 1, i.e. the amino acid sequence of such an enzyme is distinguished by the fact that it consists of a repetitive sequence of identical or very similar sequence sections composed. Each of these repetitive sequences is called a module and each module enables the enzymatic incorporation of a specific substrate into the substance synthesized by the enzyme. The products synthesized by the NRPS and KPS enzymes are often of high pharmaceutical value, such as the penicillins, vancomycins or erythromycins. The method described here enables the efficient production of new genes for modular enzymes, the gene expression of these new genes enables the production of new substances. |
isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/DE-10340068-A1 |
priorityDate | 2000-04-26-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 1328.