abstract |
A transdermal therapeutic system of the matrix type, with an active substance-impermeable backing layer, a removable protective layer and an active substance-containing matrix based on hydrophobic polymers, wherein the active substance has a melting point above room temperature and at least for a part of the duration of use of the TT in a saturation solubility Exceeding concentration is characterized in that a polyacrylate polymer is added to the hydrophobic base polymers of the active substance matrix, and / or that the matrix layer containing the hydrophobic polymers is provided with a self-adhesive skin contact layer based on polyacrylates. |