| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_ec0024795f45a646ef64b3664ab8a26d |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K2317-52
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K2317-622
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K2319-00 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P37-06
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K16-2809 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N5-18
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K16-28
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-12
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P37-06 |
| filingDate |
2000-01-14-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_99e63207c631be5cc30f043e33ea5ec1
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_b6d9b033e4bd091d50d19607f1252fdf
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_171bd06093d30ac9c43ac5f1fd47a71c |
| publicationDate |
2001-08-02-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
DE-10001372-A1 |
| titleOfInvention |
Anti-CD3 single-chain antibodies with human Cmu3 and Cmu4 domains |
| abstract |
Disclosed is a single-chain antibody characterized in that it contains (a) a human CD3-specific variable domain (scFv), and (b) its constant domains are from a human IgM molecule and the molecule 3 domain and C¶mu¶4 domain, but not the C¶mu¶1 domain and the C¶mu¶2 domain. In a preferred embodiment, the antibody of the invention contains a human IgG¶3δ hinge region between the variable and constant domains. Also described are DNA sequences encoding this antibody and expression vectors containing these DNA sequences and drugs containing the above compounds, preferably for the prevention of acute rejection reactions following organ transplantation. |
| priorityDate |
2000-01-14-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |