Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_562e4af016953c0a80e09960559ed0d2 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-6855 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-6804 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-5308 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-6809 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-6855 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-09 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-53 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-6809 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-50 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-6804 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-68 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-566 |
filingDate |
2000-09-01-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_26f870a260cd397a180dfde80a6a9308 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_06c58af0ebdb89905a642e321baacaf6 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_0ef37704bccba46a7ba7294e0a956059 |
publicationDate |
2005-11-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
DE-00959909-T1 |
titleOfInvention |
TOTAL CHROMOSOME ANALYSIS OF PROTEIN-DNS INTERACTIONS |
abstract |
A method of identifying a region of a living cell genome to which a protein of interest binds, comprising the steps of: a) linking DNA-binding protein in the living cell with genomic DNA of the living cell, wherein genomic DNA cross-linked, DNA-binding protein is produced; b) generating DNA fragments of the DNA-binding protein-associated genomic DNA in a), wherein a mixture is generated with DNA fragments to which DNA-binding protein is bound; c) removing a DNA fragment to which a protein of interest is bound from the mixture prepared in b); d) separating the DNA fragment identified in c) from the protein of interest; e) amplifying the DNA fragment of d) using a polymerase chain reaction; f) contacting the DNA fragment of e) with DNA having a sequence complementary to genomic DNA of the cell under conditions where hybridization between the DNA fragment and a region of genomic DNA is present. |
priorityDate |
1999-09-01-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |