http://rdf.ncbi.nlm.nih.gov/pubchem/patent/DD-299068-A5
Outgoing Links
Predicate | Object |
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assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_da9c519bc5d52cdf9e2c478e123d9f7b |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07J1-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07J75-00 |
filingDate | 1989-10-09-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_f34531ef1490e0bf61119a283b983a70 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_92a51a8e5ba703a1cb7c7fadb3088ebe http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_b4b400dec6cc996011db4d78d3c3c278 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_839c67c7b6920ad4ae387f381ae66a04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_a01285f558a8a9c216e4a881e06aa59c http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_3ce251a51919aa9acc8814bdddbd5ea6 |
publicationDate | 1992-03-26-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | DD-299068-A5 |
titleOfInvention | PROCESS FOR PREPARING 11 BETA-ARYL SUBSITUTED 17 BETA-ALKOXY-17 ALPHA -ALKOXYMETHYL-ESTRA-4,9-DIEN-3-ONES |
abstract | The invention relates to a chemical-synthetic process for the preparation of 11b-aryl-substituted compounds which are of interest as potential agents for the control of fertility in the pharmaceutical industry. In the process, * with bases in the 17b-alkoxides are converted, which are reacted with alkyl halides to 17b ethers and then epoxidized selectively in the * with H2O2 to the 5a, 10a epoxides, then with p-substituted Arylmagnesiumbromiden in the presence of copper I salts are opened to 11b-aryl-substituted 5α-hydroxysteroids and converted to the 11b-aryl-substituted * under acidic conditions. {Estrane; 11b-aryl substituted * 17b-ethers; Antigestagens; Drug} |
priorityDate | 1989-10-09-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 96.