| abstract |
The present invention relates to compounds of formula I wherein A, B, M, R, Ar and Het are as defined in the specific description and pharmaceutically acceptable ester and amide derivatives thereof; N-oxides thereof, tetrazole derivatives thereof and salts thereof. These compounds have valuable pharmacological effects, especially as inhibitors of thromboxane synthetase and as receptor antagonists of thromboxane A2 and prostaglandin H2. They are presented in a manner known per se. Formula {(arylsulfonamido and pyridyl or imidazolyl) -substituted carboxylic acids; Esterderivate; amide derivatives; Inhibitor of thromboxane synthetase; Receptor antagonist of thromboxane A2; Receptor antagonist of prostaglandin H2} |