| abstract |
The invention relates to a process for the preparation of the general formula II in which R represents hydrogen or an organic acid radical. These compounds are of particular interest to the pharmaceutical industry because physiologically active pregnane compounds are available via these intermediates. According to the invention, * of the general formula II in which R can be hydrogen or an organic acid residue is prepared by reacting elemental bromine in polar, aprotic solvents in the presence of catalytic amounts with the general formula I in which R has the abovementioned meaning Mineral acid are reacted. {* Bromination; Bromine, elemental; Solvent, polar, aprotic; Mineral acid, catalytic} |