abstract |
2-Substituted 4-amino-5,6,7,8-tetrahydro-7-benzyl-pyrido & 4, 3: 4,5, thieno & 2,3-d! Pyrimidines of the formula I with antianaphylactic and antihistaminergic effects can be prepared by 2-amino-3-cyano-6-benzyl-4,5,6,7-tetrahydro-thieno & 2,3-c! pyridine of the formula II with nitriles of the general formula III in which R has the abovementioned meaning, in the presence of hydrogen chloride. |