http://rdf.ncbi.nlm.nih.gov/pubchem/patent/DD-271111-A1
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_eab56e4fe8837840887f41af83e328ee |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D213-85 |
| filingDate | 1988-03-01-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_39bbce66867c1287e57182b83e447f9c http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_85fb700137e95fb97824552bb409e40b http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_b6c32a8a09553ae5c276b5b1e927da77 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_c9f124850666c3f6452be2023266dad3 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_a0cf0aabcba9bc52043494b90edab6fe |
| publicationDate | 1989-08-23-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | DD-271111-A1 |
| titleOfInvention | PROCESS FOR PREPARING SUBSTITUTED 3-CYAN-PYRID-2 (1H) -ONE |
| abstract | The invention relates to a process for the preparation of substituted 3-cyano-pyrid-2 (1H) -ones with optionally cycloaliphatic cross-linking in the 4,5- or 5,6-position. It is the object of the invention to represent these compounds in a simple manner with good yields. The task is to find a technically feasible synthetic route. The object is achieved by the reaction of substituted 3-cyano-pyrid-2 (1H) thiones with 2-bromoethanol to give the 2- (2-hydroxyethylthio) pyridine-3-carbonitriles. Subsequent heating of these compounds with alkali metal alkoxides in alkanols (C1C3) or by means of diluted alkaline solutions in conventional protic or aprotic solvents, in each case under reflux, gives the 3-cyano-2 (1H) -pyridones in very good yields. The 3-cyano-2 (1H) -pyridones can be substituted in different ways in the 4- and 6-positions or in cycloaliphatic bridged positions in 4,5- or 5,6-position. The invention has significance for the pharmaceutical and chemical industries. |
| priorityDate | 1988-03-01-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 56.