Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_76195fd1cd08192222699d8e7a88c231 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N- http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07F- http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K- http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07F9-30 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07F9-32 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07F7-08 |
filingDate |
1988-05-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_3e4e45179c53448eccaa034710eddaca http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_613eed73ccd287298af5520db8cc2146 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_286131efee002178a350277b9f10fcfc |
publicationDate |
1989-08-09-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
DD-270714-A5 |
titleOfInvention |
PROCESS FOR THE PREPARATION OF PHOSPHOROUS HMG-COA REDUCTASE INHIBITORS |
abstract |
The invention relates to a process for the preparation of phosphorus-containing compounds which inhibit the enzyme 3-hydroxy-3-methylglutaryl-coenzyme A reductase and are thus suitable as hypocholesterolemic agents. The compounds prepared according to the invention have the formula including their salts, in which R is a hydroxyl group, a lower alkoxy or lower alkyl radical; Rx is a hydrogen atom or an alkyl radical; X is an oxygen atom or the group NH, n is 1 or 2, and Z is a hydrophobic anchor. formula |
priorityDate |
1987-05-22-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |