http://rdf.ncbi.nlm.nih.gov/pubchem/patent/DD-267864-A7
Outgoing Links
Predicate | Object |
---|---|
assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_684465171e79431b5ff9cb9332417c6b |
classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K2039-522 |
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K39-0208 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K39-05 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K39-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K39-00 |
filingDate | 1986-06-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_86e8ddd557c1de668ca53eed7e440e99 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_329b03d674059c28b1885981d70b741f http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_ed2a11304639bf1c7a7379c37be3c0f9 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_37fbec0a48b09d4d82d0782fd75de19c |
publicationDate | 1989-05-17-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | DD-267864-A7 |
titleOfInvention | METHOD FOR THE PRODUCTION OF A LIVING VACCINE AGAINST LISTERIOSIS IN SHEEP AND GOATS |
abstract | In the proposed method of producing a live vaccine against listeriosis in sheep and goats, attenuated strains of the species Listeria monocitogenes are cultured in a meat-peptone broth containing 8 to 20 g / l glucose. The culture of the strain is carried out in a fermenter while maintaining the following characteristics: air from 3 to 5 l / min., Mixer from 300 to 1,000 revolutions / min, temperature of 35 to 37C, p H value of 7 to 7.6 , the quantum of Innokolums is from 1:20 to 1: 100 per working content of the fermenter. After completion of the cultivation, the biomass produced is diluted, depending on its density, with a protective medium, then homogenized and lyophilized. The lyophilization is carried out in a protective medium having a composition of 2 to 17% sodium glutamate, 5 to 20% sucrose and 0.5 to 5% of destructed gelatin. The applied lyophilization method of the vaccine ensures no less than 80% surviving cells of both serotypes. |
priorityDate | 1985-06-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 27.