abstract |
A process for the synthesis of (1R, 4S) -4-acyloxy-1-hydroxycyclopent-2-enes by enzyme-catalyzed transesterification of cis-1,4-dihydroxycyclopent-2-ene with carboxylic acid esters in organic solvents is described. These compounds serve as starting material for the synthesis of optically active prostaglandins and prostaglandin derivatives. |