| abstract |
The invention relates to a process for the preparation of novel 2-heteroaryl-5-acylaminothiazolen, which are interesting as optical brighteners, and pharmaceuticals. The aim of the invention, hitherto unknown 2-heteroaryl-5-acylaminothiazole of the formula II in which R is heteroaryl to produce in high yield and purity, was solved by heteroaryl-5-aminothiazole of formula I in geloester form with an acylating agent be implemented. Particularly suitable acylating agents are the acid anhydrides and acid chlorides, in which case an auxiliary base is added. The solvents used are the acids underlying the acylating agents, excess acylating agents themselves and aprotic solvents, preferably acetonitrile. Formula II |