http://rdf.ncbi.nlm.nih.gov/pubchem/patent/DD-259046-A1

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assignee http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_62b563909ed77d94afc3c237e0fbd935
classificationIPCInventive http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-566
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-68
filingDate 1987-04-01-04:00^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_34342675f5e80faefe4de3e0e572d4d9
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_c9c713ab6f0b4a87ed97fb79fa0e8658
publicationDate 1988-08-10-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber DD-259046-A1
titleOfInvention PROCESS FOR THE QUANTITATIVE DETERMINATION OF C-REACTIVE PROTEIN (CRP)
abstract Object of the invention is the quantitative determination of a serum protein, called C-reactive protein. Its field of application is clinical laboratory diagnostics, since the concentration of CRP in the serum and other body fluids allows conclusions about the health status of the examined patients or the health status of animals. Concentration determination is performed as a ligand assay, i. h., without the use of specific antibodies, as usual in such tests (immunoassays). By the method described here, several disadvantages are eliminated, which possess the previously performed tests. It eliminates the elaborate and the use of animal material benoetigende production of specific antisera / antibodies. There are considerable simplifications in the test execution, especially as regards the sedimentation of the samples, the test is significantly faster than the antibody assays, and finally the method is cost-effective, since the reactants can be prepared relatively easily. The method is characterized in that labeled CRP added in a constant amount competes with the sample CRP for binding to a ligand-trap conjugate. After incubation and separation of the unbound molecules, the sought concentration in the sample is obtained using a standard curve.
priorityDate 1987-04-01-04:00^^<http://www.w3.org/2001/XMLSchema#date>
type http://data.epo.org/linked-data/def/patent/Publication

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