http://rdf.ncbi.nlm.nih.gov/pubchem/patent/DD-257198-A1

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classificationIPCInventive http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N5-02
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K39-395
filingDate 1987-01-29-04:00^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_3085381d88aa2bded0aa8322b7e82bbd
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_ee5626b915b1488daa1071f1ea6cd9db
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publicationDate 1988-06-08-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber DD-257198-A1
titleOfInvention PROCESS FOR PREPARING MONOCLONAL ANTIBODY AGAINST ALKALINE PHOSPHATASE
abstract The invention relates to a method for the production of monoclonal antibodies against the marker enzyme alkaline phosphatase (AP) from calf intestine. The aim of the invention is the production of antibodies of high specificity and strong binding ability in good yields. The process according to the invention is characterized in that, in a manner known per se, spleen cells of Balb / c mice which have been immunized with calf intestinal AP are fused with X63-Ag8.653 myeloma cells in cell culture, which selects antibody-producing hybrid cells. cloned, propagated and used according to the invention for the production of monoclonal antibodies by cultivation or after transplantation. The specific hybrid clones were deposited at the Central Institute of Molecular Biology (List 1987) at the following numbers: E1-D3A7 E1-F9F5 E1-H7E8A field of application of the invention is the most varied areas of the life sciences, including medicine.
priorityDate 1987-01-29-04:00^^<http://www.w3.org/2001/XMLSchema#date>
type http://data.epo.org/linked-data/def/patent/Publication

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