http://rdf.ncbi.nlm.nih.gov/pubchem/patent/DD-254593-A1
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_da9c519bc5d52cdf9e2c478e123d9f7b |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N5-02 |
| filingDate | 1986-12-15-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_fce9bd51bf110bb7e2aef06c8fd2f80d http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_1542adea5061c52b1b57e0c9f959233c http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_14f6a6e9bb301ba819f6330591167327 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_5eeead31b457ecf413aec76bc4185675 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_92fb39d227e6af8551cae8ccf344d640 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_696c26fdfeeafbb123c5507119cbd8fc http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_61cd521774d0011f42c3002a1308e889 |
| publicationDate | 1988-03-02-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | DD-254593-A1 |
| titleOfInvention | PROCESS FOR THE PREPARATION OF MONOCLONAL ANTIBODY AGAINST HUMAN INTERFERON ALPHA |
| abstract | The invention relates to a method for obtaining monoclonal antibodies which are capable of reacting with human interferon-alpha (HuIFN-alpha). The object of the invention is to produce monoclonal antibodies which are suitable for immunochemical determination and for immunaffinitaetschromatographic enrichment of HuIFN-alpha. The method according to the invention is characterized in that spleen cells of mice which have been intrinsically immunized with HuIFN-alpha are fused with myeloma cells of the line P3-X63-Ag8.653 in vitro, the hybridomas obtained are selected with specific antibody production, followed by single-cell cloning by means of a special micromanipulator performed and the clones obtained in a conventional manner further propagated. According to the process of the invention, the monoclonal antibodies ZIMET B61D3 and ZIMET C61D2 are obtained by cultivating the hybrid cell clones H / B61D3 and H / C61D2. Fields of application of the invention are human medicine, veterinary medicine and biotechnology. |
| isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-111087461-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-8349331-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-8557967-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-7910707-B2 |
| priorityDate | 1986-12-15-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 25.