| abstract |
The invention relates to derivatives of 14-O - & (1-amino-2-methylpropan-2-yl) thioacetyl! Mutilin and -19,20-dihydromutilin, in particular N-acyl-14-O - & (1-amino-2 -methylpropan-2-yl) thioacetyl! mutilin or -19,20-dihydromutilin, in particular new pleuromutilin derivatives of the formula I, wherein R 1 is ethyl or vinyl and R 2 is an aminoalkyl group whose alkyl moiety may be substituted by hydroxy or a five-membered one Heterocycle, and their acid addition and quaternary salts, as well as processes for their preparation and their use. Formula I |