http://rdf.ncbi.nlm.nih.gov/pubchem/patent/DD-253249-A1
Outgoing Links
Predicate | Object |
---|---|
assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_c9b262c842f9c7f3c38a61e1f2d892f1 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07J1-00 |
filingDate | 1986-10-13-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_8266329a08c7c6302d78fe156232e751 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_6ccf76bb2a8217f1e2e7b0734d7aac61 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_890c4d8ae474a093f174e0ebd0e2e897 |
publicationDate | 1988-01-13-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | DD-253249-A1 |
titleOfInvention | PROCESS FOR THE PREPARATION OF STEROID-16 ALPHA, 17 BETA DIOLES |
abstract | The invention relates to a process for the preparation of steroid 16a, 17b-diols, in particular estriol. This product is a highly effective estrogenic drug used as an active ingredient in ampoules and / or tablets for the treatment of climacteric deficiency symptoms. According to the novel procedure, steroid 16a, 17a-epoxy-17b-acetates of the general formula I wherein R1 CH3, C2 H5 R2 OH, OAc; O benzoate; O-propionate; OCH3, with an alkali metal borohydride in the presence of an inorganic base and organic solvents or solvent mixtures to steroid 16a, 17b-diols of the general formula II in whichR1CH3, C2H5R2OH, OCH3 meant. |
isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2012032529-A1 |
priorityDate | 1986-10-13-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 29.