http://rdf.ncbi.nlm.nih.gov/pubchem/patent/DD-253184-A1
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_eab56e4fe8837840887f41af83e328ee |
| classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/Y02A50-30 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K39-112 |
| filingDate | 1986-10-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_e5990f507e4c9d2060da12050867a521 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_4ab0fc066bfb37d070f5fab250f77255 |
| publicationDate | 1988-01-13-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | DD-253184-A1 |
| titleOfInvention | METHOD FOR PRODUCING STABLE SALMONELLA VACCINE STEM WITH AN ATTENANCE TREATMENT ADJUSTED TO ANY OF THE INDUSTRY SPECIES |
| abstract | The invention relates to a method for the production of live vaccines for farm animals from stable Salmonella typhimurium one-, two- and Dreimarker Impfstaemmen in any desired - on Maeusemodell between i. p. LD50102.5 to 10 7 to 107 (wild strain 101) germinating buds - attenuation levels adapted to the host species; by using in vitro non-responders or aspartic acid auxotrophy cloning different virulence reduction as a single-marker vaccine; in which a second and / or third attenuating mutation is incorporated when needed (and when asp-clones with reversion frequencies 10 7 are used), namely a first or colored marker (DD-WP 218 836 A 1 and DD-WP announced) -Stickwechselrift drift marker (eg, functionally modified RNA polymerase or gyrase DD-WP 155 294) for the purpose of increasing the stability (potentiation of individual Stabilitaeten) to values 10 14 or 10 21Verminderung or loss of potency for Impfstamm-Infektkettenbildung than Sequence of impaired outer membrane permeability (according to WHO definition: Attenuation marker) Sets the attenuation level to the respective optimal value. |
| priorityDate | 1986-10-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 26.