http://rdf.ncbi.nlm.nih.gov/pubchem/patent/DD-249482-A1
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_3bfedd8ba4800708cecfd357707f8f67 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07F9-38 |
| filingDate | 1986-05-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_d71cbd8e35b8b9462dcfe18c4f6b74dd http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_315bc8080d208fc33da84e1f529b547c |
| publicationDate | 1987-09-09-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | DD-249482-A1 |
| titleOfInvention | PROCESS FOR PREPARING FORMAMIDINOMETHANE-BISPHOSPHONIC ACID AND AMINOMETHANE-BISPHOSPHONIC ACID |
| abstract | It is an object of the invention to provide a process by which formamidinomethane and aminomethane bisphosphonic acid can be prepared in high yields from starting materials which are technically easily accessible, cheap and, if possible, without the use of chlorine-containing and highly toxic starting materials which require a high level of safety. The object of the invention is the development of a process with which phosphoric (III) oxide (P4O6), phosphoric acid and formamide can be used to produce formamidinomethane and aminomethane bisphosphonic acid in high yields. According to the invention, a mixture of P4O6, anhydrous H3PO4 and formamide having a molar ratio between 1: 1: 1 and 1: 3: 3 is reacted at 300 K to 400 K and the reaction mixture is hydrolyzed with water or an inorganic acid, and the formamidinomethanebisphosphonic acid formed crystallizes out the solution is isolated, or-hydrolyzed in a conventional manner in an alkaline solution and the Aminomethanbisphosphonsaeure isolated by crystallization from an acidic solution. Yields of 75% to 85% are obtained. |
| isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/DE-3700772-A1 |
| priorityDate | 1986-05-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 42.