| abstract |
The invention relates to a process for the preparation of novel quinolones for use as medicaments. The aim of the invention is the provision of new compounds with valuable pharmacological properties, in particular with antihypertensive action. According to the invention, novel quinolones of general formula I are prepared in which X is the radical of an optionally substituted benzene ring; R is lower alkyl; R3 is hydrogen or lower alkyl; R1 and R2, which may be the same or different. Are hydrogen, lower alkyl or together with the nitrogen atom to which they are attached form a 5- to 7-membered saturated heterocyclic ring optionally containing another heteroatom selected from nitrogen, oxygen and sulfur and optionally substituted by 1 or more lower alkyl groups ; and the dashed line between positions 2 and 3 of the quinolone nucleus is an optional bond. Formula I |