http://rdf.ncbi.nlm.nih.gov/pubchem/patent/DD-246540-A1
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_3bfedd8ba4800708cecfd357707f8f67 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D231-32 |
| filingDate | 1986-03-14-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_348d9e5cfcca10de4cdddd6f3d16f882 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_e0c5dd37f36ba4c5036e9ac04e93af96 |
| publicationDate | 1987-06-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | DD-246540-A1 |
| titleOfInvention | PROCESS FOR PREPARING 1-SUBSTITUTED 3-CARBOXYALKYLOXY-PYRAZOLIN-5-ONEN |
| abstract | The invention has the aim of obtaining the title compounds and their salts in high yields in a technically very simple manner. The previously unknown title compounds and their physiologically acceptable salts serve as antiphlogistics and antisclerogenic cardiovascular drugs. The object is achieved according to the invention by means of a hitherto unknown, surprisingly simple synthesis principle, namely the simultaneous introduction of a carbonyl function in the 5-position and a bromo substituent in the 4-position of the pyrazole ring of 1-substituted 3-carboxyalkyloxy-pyrazoles in an aqueous-alkaline medium at reaction temperatures around 20C by means of bromine and optionally the reductive replacement of the 4-bromo substituent by hydrogen in an aqueous-alkaline medium at reaction temperatures around 20C using inexpensive technical reducing agents, for example sodium sulfite. |
| priorityDate | 1986-03-14-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 49.