http://rdf.ncbi.nlm.nih.gov/pubchem/patent/DD-241750-A1
Outgoing Links
Predicate | Object |
---|---|
assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_3bfedd8ba4800708cecfd357707f8f67 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-15 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N5-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N5-02 |
filingDate | 1985-10-15-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_4cf231b0f09a9c2a776d2f2ecca77151 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_da74ba0f22a1f728b89415fee82ce000 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_8c9c101db7f416b7b09f36b860020835 |
publicationDate | 1986-12-24-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | DD-241750-A1 |
titleOfInvention | PROCESS FOR THE QUANTITATIVE DETERMINATION OF LD DEEP 50 |
abstract | The invention relates to a method for the quantitative determination of LD50 and is used in the pharmaceutical industry and in pharmacology. The aim of the invention is to provide a novel test method for the quantitative determination of the LD50 on the basis of the cell culture determined inhibitory concentration 50 (IC50), which is generally applicable. The task is to test the cytotoxic effect of a number of newly developed active ingredients. The object was achieved by using a calf aortic endothelial cell line BKEz-7 and applying the general (nonspecific) cytotoxicity test. The method of the invention is also suitable for comparison of other cell types and cell types or cell performances with the LD50 for the purpose of predicting LD50 estimates. |
priorityDate | 1985-10-15-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 57.