| abstract |
The invention provides a process for the preparation of substituted 3,4-diamino-1,2,5-thiadiazole compounds of the general formula (I) in which A, Z, m, n and R 1 have the meanings indicated, and the non-toxic pharmaceutically acceptable Salts thereof. These compounds are prepared by ring closure of a substituted Ethandiimidamids of the general formula (II). The compounds of the invention are histamine H2 receptor antagonists and are novel anti-ulcer agents. Formula I, II |