http://rdf.ncbi.nlm.nih.gov/pubchem/patent/DD-239795-A5
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_3e9445e5e3626f36e932c6451a928250 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-395 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D498-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D498-08 |
| filingDate | 1985-11-07-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_a694312ca509e82049010caf5af76d09 |
| publicationDate | 1986-10-08-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | DD-239795-A5 |
| titleOfInvention | PROCESS FOR PREPARING SUBSTITUTED 4-BENZYL-PIPERAZINYL COMPOUNDS |
| abstract | The invention relates to a process for the preparation of substituted 4-benzyl-piperazinyl compounds having high antibiotic, in particular antituberkulöser efficacy for use as medicaments. The aim of the invention is the provision of new substituted 4-benzyl-piperazinyl derivatives having a longer duration of action. According to the invention, novel substituted rifamycin compounds of the formula are prepared, in particular 3-W-rifamycin SV and S compounds, wherein W is a piperazin-1-yl radical of the formula (II) in which R1 and R2 are C (1-4 ) Alkyl and R3, R4 and R5 are hydrogen or C (1-4) -alkyl, or R2 together with R3 or R3 together with R4 optionally substituted by C (1-4) -alkyl substituted buta-1,3-diene 1,4-ylene, trimethylene or tetramethylene, in which case R1, R4 and R5 or R1, R2 and R5 denote hydrogen or C (1-4) -alkyl, and their salts. Formulas (I A), (I B), (II) |
| isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-0284552-A1 |
| priorityDate | 1985-11-07-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 61.