http://rdf.ncbi.nlm.nih.gov/pubchem/patent/DD-237067-A3
Outgoing Links
Predicate | Object |
---|---|
assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_3bfedd8ba4800708cecfd357707f8f67 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07J51-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07J9-00 |
filingDate | 1984-12-14-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_6d136fb1d0140ceaffc9942b90be28e2 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_99d4fb35a384d99b3d328e8a2621f420 |
publicationDate | 1986-07-02-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | DD-237067-A3 |
titleOfInvention | METHOD FOR THE PRODUCTION OF MULTIPLY SPECIFICALLY TRITIUM MARKED CHOLESTEROL |
abstract | The invention serves to produce tritium-labeled cholesterol which is increasingly used in medical institutions as a tracer for pharmacological examinations, preferably of lipid metabolism, obesity and associated cardiovascular diseases. The aim of the invention is to provide a method which provides multiple specific labeled cholesterol in a simple synthesis. According to the invention, the object is achieved by dehalogenating 2-brominated 6b-bromo-cholestenones, which are readily accessible steroid ketones, which are stable and storable in crystalline form at room temperature, in solvents in the presence of Pd / CaCO3 with T2, either triply or in the presence of T2 double-labeled cholest-4-en-3-one according to the method of Collins and Hobbs (Aust. J. Chem. 18 (1965) 1049) via the appropriately labeled 6b-bromo-cholest-4-en-3-one in either triplicate or double labeled cholesterol is delivered. |
isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-1285902-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-1285902-A4 |
priorityDate | 1984-12-14-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 40.