| abstract |
The invention relates to a process for the preparation of novel 3-mercapto-1,2,4-triazacycloalkadienderivate for use as a medicament. The aim of the invention is the provision of new compounds with analgesic properties, in particular for the treatment of painful-inflammatory diseases of the rheumatic type. According to the invention, 3-mercapto-1,2,4-triazacycloalkadiene derivatives of the formula I in which, for example: R 1 and R 2 independently of one another are unsubstituted or substituted aryl or optionally N-oxidized heteroaryl radicals, n is 0, 1 or 2 and R 3 is a substituted aliphatic hydrocarbon radical and their salts are prepared in such a way by z. B. from a compound of formula II, wherein one of Y1 and Y2 is a leaving group Y and the other is a hydrogen atom and Y3 and Y4 together represent an additional bond, or split off from a salt thereof with the introduction of an additional bond HY. |