| abstract |
The invention relates to the production of an oral vaccine against viruses, such as influenza viruses, and against other pathogens. The goal is the production of an oral vaccine against different pathogens of infections, with the easy-to-use combination of the manufacturing steps enabling an economic procedure and achieving an application-friendly end-use form. The object is achieved by inactivating the corresponding germs in combination chemically / physically or chemically or only physically or by relevant Inaktivierungsarten using protective materials from the substrate, these inactivated germs are added with an additional protective colloid, the suspension in this state below 0C is cooled and lyophilized and the resulting lyophilisate is finally placed in enteric-coated capsules, suppositories or other Einschluesse. This work also includes other modifications (active or mixed active / inactive form). The field of application is the production of oral vaccines and selected biopraparates for human and veterinary medicine. |