http://rdf.ncbi.nlm.nih.gov/pubchem/patent/DD-221365-A1
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_da9c519bc5d52cdf9e2c478e123d9f7b |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K9-30 |
| filingDate | 1983-11-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_021e152b4bb645491d10068f7a0e9784 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_d3d4625cd22f695501071f82d91f2983 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_51405ea0e0fd73eb1e293ced004bad11 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_4e5a39ad53cdca35034699c9004ce7c4 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_ba81d61c1540d27af360067452404c14 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_a4a054c8da9733a2bf8666575f890d0e |
| publicationDate | 1985-04-24-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | DD-221365-A1 |
| titleOfInvention | METHOD FOR THE PRODUCTION OF DRUGS WITH DELAYED ACTIVE SUBSTANCE |
| abstract | The aim of the invention is to produce effective pharmaceuticals using per se known technologies for the preparation of pharmaceutical preparations with delayed release of active substance in or from the colon region, which at the same time create a favorable intestinal milieu for the effect. The invention has for its object to show process conditions for the preparation of these pharmaceutical preparations, in particular with regard to the structure and constituents of the core and cladding layer. According to the invention, the object is achieved by incorporating substances influencing the colon milieu, in the main buffer substances, organic acids, carbohydrates and / or enzymes, into the preproatum core containing active substance and / or into a coating layer. The coating layer, consisting of cross-linked low-ester pectin, fat, modified fat and / or pseudo-fat, ensures the release of the drug in the colon area. As low-esterified pectin, apple or citrus pectin has proven to have a defined degree of esterification. As the envelope-degrading enzymes, pectin and fat-splitting enzymes are used. |
| isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-114230815-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-114230815-B |
| priorityDate | 1983-11-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 144.