http://rdf.ncbi.nlm.nih.gov/pubchem/patent/DD-217218-A1
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_334f3ee6eeb9c496c3cce8c9fc4532f0 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D277-54 |
| filingDate | 1983-09-12-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_2d8d0a8c10fe158121dc84e98f84dd26 |
| publicationDate | 1985-01-09-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | DD-217218-A1 |
| titleOfInvention | PROCESS FOR PREPARING SUBSTITUTED 4-AMINO-1,3-THIAZOLENE |
| abstract | The present invention relates to a process for the preparation of substituted 4-amino-1,3-thiazoles, which are already partially known. The representatives of this class of substances are pharmaceutically interesting compounds that can also be used as starting materials for the synthesis of other potential drugs. Due to a surprising, unexpected reaction process bypasses the already known synthetic variants for the preparation of 4-amino-1,3-thiazoles and leads because of the cheap starting materials and the good yields at the same time in an economically favorable synthesis principle. The aim of the invention is to make the class of 4-amino-1,3-thiazoles accessible by a new, generalizable method. The object is achieved by reacting N-nitroguanyl-dithiocarbimic acid monoesters in the presence of alkali metal hydroxides with benzyl halides bearing electron acceptor groups in polar, aprotic solvents at temperatures between 10 C and 80 C. The intermediates are conveniently isolated without further purification. |
| priorityDate | 1983-09-12-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 32.