| abstract |
An animal feed containing the actaplanin antibiotic A-4696 or its novel factors B deep 1, B deep 2, B deep 3, C deep 1 a, C deep 3 and E deep 1, obtained by cultivating an ATCC 31680 strain, is described , ATCC 31682 or ATCC 31683 of Actinoplanes missouriensis in a fermentation medium containing commonly assimilable sources of carbohydrate, nitrogen and inorganic salts, under submerged aerobic fermentation conditions, to the formation of a substantial amount of antibiotic activity, and subsequent separation known per se obtained complex of the antibiotic A-4696 in the respective factors. These factors are effective antibacterial and antimicrobial agents, which are useful inter alia as growth-promoting and feed-improving agents in poultry, swine, sheep and cattle (repulping). |