http://rdf.ncbi.nlm.nih.gov/pubchem/patent/DD-203548-A1
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_da9c519bc5d52cdf9e2c478e123d9f7b |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07J19-00 |
| filingDate | 1982-02-12-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_fd4d21ee8f419dd867154b4623e81531 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_c84b6f12a22119918e5e2df6a8a30c59 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_25f86e341bbee112f41e5b2f65fdaf46 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_390b7ed81961372e31277aa0f0db0b6b |
| publicationDate | 1983-10-26-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | DD-203548-A1 |
| titleOfInvention | PROCESS FOR PREPARING C22- (3'-OXO-PROP-L-EN-L-YL) -CARDENOLIDES |
| abstract | The invention relates to a process for the preparation of C22- (3'-oxo-prop-1'-en-1'-yl) -cardenolides of the general formula I (cf Appendix), which can be used in the pharmaceutical industry. The aim of the invention is to introduce a multiply conjugated system incorporating the lactone ring into cardiac active steroids. According to the invention, 22-allyl cardenolides are oxidized in dioxane with selenium dioxide at boiling heat (ratio cardenolide: selenium dioxide = 1: 7.5,). The compounds I prepared (R = COCH 3 and I (R = (D-digitoxose) & ind 3) show a relatively good inhibiting activity in the ATPase test. |
| priorityDate | 1982-02-12-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 23.