| abstract |
The invention relates to a process for the preparation of novel beta-lactam compounds, which are distinguished by an antibacterial and beta-lactamasehemmende effect. To produce carbamides, thioureas and selenoureas, an amino-beta-lactam compound dissolved in a mixture of acetonitrile and triaethylamine is reacted with a corresponding isocyanate or isoselenocyanate. Other possible compounds are the 7? -Phenyl-acetamido-3-chloro-3-cefem-4-carboxylic acid triaethylammonium salts. |