http://rdf.ncbi.nlm.nih.gov/pubchem/patent/DD-202290-A5

Outgoing Links

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filingDate 1981-12-14-04:00^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_2a60614a715eb2ffdc071c66e9bac215
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_fbe5946a94de04849cffbfe472382bf1
publicationDate 1983-09-07-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber DD-202290-A5
titleOfInvention PROCESS FOR THE PRODUCTION OF INDOIND DERIVATIVES
abstract The invention relates to a process for the preparation of indole derivatives for use as medicaments, for example for the treatment of thrombosis, ischemic heart disease, stroke, migraine, cancer and Gefaesskomplikationen in diabetes. The object of the invention is to provide compounds which selectively inhibit the action of thromboxane synthase without inhibiting the action of prostacyclin synthase. According to the invention, compounds of the formula I are prepared in which R is hydrogen, C is C 1-C 4 -alkyl, C 3-C is deeply C-7-cycloalkyl or phenyl, R 2 is hydrogen, C 1-C deep is deep 4-alkyl ; C 1 to C deep 4-alkoxy or halogen; R is high, 3 is hydrogen or C is deep C 1 -C 4 -alkyl; X - (CH deep 2) deep n-, where n is 1,2 or 3, -CH deep 2 -CH- or -CH deep 2; Y is -COOH, -COO (C deep 1-C deep 4-alkyl, -CONH deep 2, CN or 5-tetrazolyl, and Z is 3- or 4-pyridyl, and their pharmaceutically acceptable salts.
priorityDate 1980-12-15-04:00^^<http://www.w3.org/2001/XMLSchema#date>
type http://data.epo.org/linked-data/def/patent/Publication

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