| abstract |
The invention relates to a process for the preparation of di- or trisubstituted xanthines with neuroleptic properties for use as medicaments. The aim of the invention is to provide novel xanthines with a sedative and anxiety-relieving effect. According to the invention, xanthines of the formula or their physiologically tolerable salts are prepared. In the formula: R 1 deep alkyl in C deep 1-C deep 4, isoalkyl in C deep 3-C deep 4, CH deep 2- (alkenyl in C deep 2-C deep 3) or CH deep 2- (isoalkenyl in C deep 3), R deep 3 alkyl in C deep 3-C deep 5, isoalkyl in C deep 3-C deep 5, CH deep 2- (alkenyl in C deep 2-C deep 4), R deep 8 H, Methyl or ethyl, except that 1) when R is 8 H deep, R is low 1 allyl, and 2) R deep 1 and R deep 3 are not simultaneously butyl or allyl. |