| abstract |
The invention relates to the PS DD-WP 139715 and relates to a process for the preparation of the abovementioned compounds of the general formula I and II. The aim is to produce biologically active 1,4,7,9-disubstituted 4,5-dihydroxy s-triazolo (4,3-a) quinazolin-5-ones. According to the invention, the compounds are prepared by reacting substituted 2-hydrazino-3,4-dihydro-quinazolin-4-ones with optionally activated saeder derivatives under oxidative cyclization or under melting conditions or in organic solvents. The compounds of general formula I, II and their intermediates are possible diuretics and antianaphylactics. The field of application of the invention is the pharmaceutical industry. |