abstract |
The invention relates to a process for the preparation of 7-oxo-1-azabicyclo (3,2, O) hept-2-ene-2-carboxylic acid derivatives having a strong antibacterial activity for use as medicaments. The aim of the invention is the provision of new stable antibacterial compounds. According to the invention, compounds of the general formula (I) are prepared in which, for example: R 1 is hydrogen or an optionally substituted alkyl group; X is an oxy group, thio group, sulfinyl group, and the like; A is a bi- or trivalent, saturated aliphatic hydrocarbon group; p 1 or 2; R 2 represents an azido, nitro or cyano group, etc .; m and n are the same or different, 0 or 1. |