| abstract |
The invention relates to a novel synthesis process of pyridine derivatives of the formula I wherein R 1 is an alkyl or an alicyclic group, R 2 is low and R 3 is lower alkyl, alicyclic groups or a heterocyclic compound with the nitrogen atom to which they are attached form, wherein the process is characterized in that one uses as starting material a product of formula II, which is carried out successively two substitution reactions of the radical -CH deep 2 - to obtain the corresponding substituted nitrile and then the hydrolysis of the nitrile function of the obtained product to obtain the corresponding amide. |