| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_5922cbe7c65a9136f85906fa09e7c967 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C51-50
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P29-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C51-487
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C57-40
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P25-04
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P7-02 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C213-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C59-52
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P25-04
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C215-10
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P29-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C59-64
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C51-487
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C229-34
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-205
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P7-02
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07B57-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C67-00 |
| filingDate |
1980-07-04-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_d6f848c3045292e6a7be6526c94346cf |
| publicationDate |
1982-01-06-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
DD-153367-A5 |
| titleOfInvention |
METHOD OF REMOVING D-2- (6-METHOXY-2-NAPHTHYL) PROPIONE ACID |
| abstract |
The invention relates to a process for separating d-2- (6-methoxy-2-naphthyl) -propionic acid with valuable pharmacological, especially anti-inflammatory, analgesic and antipyretic properties from a mixture of d- and l-2- (6-methoxy) 2-naphthyl) propionic acid. The aim of the invention is an improvement of the production process of d-2- (6-methoxy-2-naphthyl) propionic acid. According to the invention, a mixture of d- and 1-2- (6-methoxy-2-naphthyl) -propionic acid and N-R-D-glucamine is prepared in an inert solvent. The salt of d-2- (6-methoxy-2-naphthyl) -propionic acid with NRD-glucamine is less soluble in the inert solvent at the crystallization temperature than the salt of 1-2- (6-methoxy-2-naphthyl) -propionic acid with the NRD-glucamine. A salt product consisting of d-2- (6-methoxy-2-naphthyl) -propionic acid with N-R-D-glucamine crystallizes out. This is dissolved in an inert solvent and recovered therefrom by crystallizing d-2- (6-methoxy-2-naphthyl) -propionic acid, which may optionally be converted to a pharmaceutically acceptable salt. |
| priorityDate |
1979-07-06-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |