http://rdf.ncbi.nlm.nih.gov/pubchem/patent/DD-151755-A5
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_ad3d51747a2eba1e7636894263252df4 |
| classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/Y02A50-30 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D241-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D207-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D471-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D- http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-395 |
| filingDate | 1980-06-26-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_5addcee749680f61b3e26ae92d1a277d http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_c41ab573afd48256e0fdb5759cadc5d0 |
| publicationDate | 1981-11-04-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | DD-151755-A5 |
| titleOfInvention | PROCESS FOR PREPARING 8-ETHYL-5-OXO-5,8-DIHYDRO-PYRIDO (2,3-D) PYRIMIDINE-6-CARBON ACID |
| abstract | The invention relates to a process for the preparation of 8-ethyl-5-oxo-5,8-dihydro-pyrido (2,3-d) -pyrimidine-6-carboxylic acids having valuable pharmacological, in particular antibacterial properties. Goal d. Erfindg. is d. To provide an improved simple and economical process which gives high yields. According to the invention, compounds of the general formula I in which R is a pyrrolidino or piperazino radical are prepared by reacting a 4-aminopyrimidine derivative of the general formula II in which Z represents a methylsulfonyl or methylsulfinyl radical with piperazine or pyrrolidine to give a compound of the formula general formula (A) condensed, these to a compound of general formula (B) ethylated, these with Ethylethoxymethylencyanoacetat to a compound d. general formula (C) condensed and cyclized in the absence or presence of a solvent and hydrolyzed in an alkaline medium. Regarding d. Formula II, (A), (B) (C) is referred to the description-Formula I, II, A to C - |
| priorityDate | 1979-06-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 51.