http://rdf.ncbi.nlm.nih.gov/pubchem/patent/DD-150058-A1
Outgoing Links
Predicate | Object |
---|---|
assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_9fd7675528de8388cb9d3ba48c8c8402 |
classificationIPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D243-24 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D243-26 |
filingDate | 1980-04-01-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_ec106eb809d08d280e6c82facfc54abf http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_f40eeb50a4b12457227df4d82e6ce45f http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_9392aa636beca5a919598e9254237eec http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_59928ab3e5bc3b833d4129b22f7f721c http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_32dd9f449cb559b02c0c9aead6e3b22d |
publicationDate | 1981-08-12-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | DD-150058-A1 |
titleOfInvention | PROCESS FOR THE PREPARATION OF 3-HYDROXY DERIVATIVES OF 1,4-BENZODIAZEPIN-2-ONE |
abstract | The invention relates to a process for the preparation of 3-hydroxy derivatives of 1,4-benzodiazepine-2-ones of the general formula I, in which R is a hydrogen or chlorine atom, for use as medicaments, in particular as tranquilizers. The aim of the invention is a simple and economical process for the preparation of these compounds. According to the invention, they are prepared starting from new 7-chloro-1,3-dihydro-3-hydrazino-1,4-benzodiazepin-2-ones of general formula II, in which R has the above meaning, by reaction with sodium nitrite (NaNO & ind 2% in hot salt or sulfuric acid medium at a temperature of -5 to 0 ° C. |
priorityDate | 1980-04-01-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 32.