http://rdf.ncbi.nlm.nih.gov/pubchem/patent/DD-142054-A1
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_ea2e1d5ee70989ddb542b69ded7cf5d1 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_5f2c548ed7f58bd8412f164b4e0a1dcb http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_6da054aa64642c2eba10952c44a085f2 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_a71de2537b8dab47832e0addb4fd8f18 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07J7-00 |
| filingDate | 1979-03-01-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_7a4594dbb8f25ad5e4fe05aa8de712f4 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_c8305dcbd536d10b80a27db0eae5af64 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_7ccdf43636d375bdd34734a66dcdc266 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_71d6383e85813bfafda439dd1b672c30 |
| publicationDate | 1980-06-04-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | DD-142054-A1 |
| titleOfInvention | PROCESS FOR PREPARING 17 ALPHA-HYDROXY-PREGNA-1,4-DIEN-3,20-DION |
| abstract | The invention relates to a process for the preparation ofn17a-hydroxy-pregna-1,4-diene-3,20-dione as the starting materialnfor the synthesis of corticosteroids of importance. Goal andnThe object of the invention is the chemical conversion ofnBis-nor-chola-1,4-dien-3-one ~ 22-acid, which consists of various sterolsndue to microbial side chain degradation, to that mentionednTitle compound. The process starts from the bis-nor-chola-1,4-dien3-one 22 acidnmade with lead tetraacetate and iodine in boilingnCarbon tetrachloride irradiated to 20-iodo-pregna-1,4-diene3-ηηnis implemented. This provides when heated with lithium carbonatenand lithium bromide in dimethylformamide with elimination of hydrogen iodidenthe pregna-1,4,17 (20) -trien-3-one, which is at room temperaturenin tert-butanol with N-methylmorpholine-N-oxide peroxide in the presence ofncatalytic amounts of osmium tetroxide and pyridinen17a-hydroxy-pregna-1,4-diene-3,20-dione. |
| priorityDate | 1979-03-01-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 55.